Endocrine Abstracts

Introduction: Langerhans cell histiocytosis (LCH) is a rare disease characterized by non-specific granulomatous deposits in many tissues. The hypothalamic-pituitary region is infiltrated in 5 to 50% of patients with LCH but most often in those with the multifocal form. Diabetes insipidus (DI), the most common hormonal abnormality, occurs in 15–50% of patients. Anterior pituitary deficiency occurs only in 5 to 20% of patients. We report the case of a patient with LCH who h...